AICAR, or 5-Aminoimidazole-4-carboxamide ribonucleotide, is a synthetic compound that has been studied for its potential effects on cellular processes related to energy metabolism. AICAR is an analog of adenosine monophosphate (AMP) and is known to activate AMP-activated protein kinase (AMPK), an enzyme that plays a role in cellular energy homeostasis.
Activation of AMPK by AICAR is believed to mimic the effects of exercise on cellular energy regulation, leading to increased glucose uptake and fatty acid oxidation. Due to its potential impact on energy metabolism, AICAR has been studied in the context of conditions related to metabolic disorders, such as diabetes and obesity.
It's important to note that AICAR is not approved for medical use in many countries, and its use in sports and bodybuilding is controversial. The World Anti-Doping Agency (WADA) has listed AICAR as a prohibited substance in sports.
As of my last knowledge update in January 2022, further research may have been conducted on AICAR, and it's advisable to consult the latest scientific literature for any developments. If you have specific health concerns or interests in AICAR, it is recommended to consult with a healthcare professional who can provide personalized advice based on the most current information
| Product Name: | AICAR |
| Synonyms: | 5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside,98%;5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosideAICAR;5-Aminomidazole-4-carboxamide-1-β-D-ribofuranoside;ACADESINE;AICAR;AICA-RIBOSIDE;AMPK;1-Deoxy-1-[(4-carbamoyl-5-amino-1H-imidazole)-1-yl]-β-D-ribofuranose |
| CAS: | 2627-69-2 |
| MF: | C9H14N4O5 |
| MW: | 258.23 |
| EINECS: | 220-097-5 |
| Product Categories: | ARASINE;Cardiovascular APIs;PI3K/Akt/mTOR;Akt;mTOR;PI3K;Bases & Related Reagents;Carbohydrates & Derivatives;Nucleotides;Protein Kinase |
| Description | AICAR (2627-69-2) activates AMP-activated protein kinase (AMPK). Promotes ligand-independent activation of the insulin receptor.1 Promotes skeletal muscle autophagy via activation of FoxO3a.2 Controls smooth muscle cell hyperproliferation in vascular disease.3 ?Induces osteogenic differentiation in mesenchymal stem cells.4 Inhibits proinflammatory response in glial cells.5 Cell permeable. |
| Chemical Properties | Solid |
| Originator | AICA,BIOMOL |
| Uses | glucose uptake stimulant; AMPK activator |
| Uses | AICAR is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) hav e been recognized for therapeutic potential in myocardial ischemia. Cardioprotective. |
| Uses | 5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside is used as a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle. |
AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is a synthetic compound that has been studied for its potential effects on cellular processes related to energy metabolism. AICAR is not typically available in the form of over-the-counter pills or supplements for general use. Instead, it is a substance that has been used in research settings to investigate its impact on cellular energy regulation.
In scientific studies, AICAR is often administered directly to cells or animals for research purposes to explore its potential therapeutic applications, particularly in the context of metabolic disorders such as diabetes and obesity. The use of AICAR in a supplement form for human consumption is not common, and it's important to note that its safety and efficacy for such purposes have not been well-established.
If you come across products marketed as "AICAR pills" or similar, it's essential to approach them with caution. The availability of AICAR as a dietary supplement may not be legal or regulated, and the safety of self-administering such substances is uncertain.
Quality: Purity above 99%, directly produced by the manufacturer, can accept quality testing, and can also customize any content of powder, liquid, oil, etc.
Transport: We can accept sea freight, air freight, and express delivery, with a guarantee time of 1-2 weeks and a customs clearance rate of over 99%. Even if the goods are detained, you can resend the freight and I will resend the goods.
Service: We can provide sterile water for you to directly mix and inject freeze-dried powder. In addition to powder, we also have liquids, water-based agents, oils, tablets, and professional customized synthesis routes. We provide you with professional guidance on product use, product synthesis, and product customization.
Price: We do not engage in price wars. Our first quotation may seem too expensive to you, please don't lose heart. Firstly, our quality can be guaranteed; Secondly, our transportation efficiency and customs clearance rate can be guaranteed; Thirdly, we will provide you with the highest quality service, in any aspect. If you have any questions, I will have the answer.
Q1: Can I get some samples?
A:Yes, we can supply the free sample, but the shipping cost be paid by our customers.
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Q4:Is there a discount?
A:Different quantity has different discount.
Q5: How do you treat quality complaint?
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quality problem caused by us, we will send you free goods for replacement.
Q6:Do you Accept Sample Order?
A:Yes, we accept small order from 2mg, 5mg and 10mg to evaluate quality of our goods
