• powder Exemestane CAS 107868-30-4 ,99% pure
  • powder Exemestane CAS 107868-30-4 ,99% pure
  • powder Exemestane CAS 107868-30-4 ,99% pure
  • powder Exemestane CAS 107868-30-4 ,99% pure
  • powder Exemestane CAS 107868-30-4 ,99% pure
  • powder Exemestane CAS 107868-30-4 ,99% pure
  • powder Exemestane CAS 107868-30-4 ,99% pure
  • powder Exemestane CAS 107868-30-4 ,99% pure

powder Exemestane CAS 107868-30-4 ,99% pure

No.CAS 107868-30-4
Exemestane was launched in US and other countries for the treatment of estrogendependenttumors and postmenopausal breast cancer. It is a novel steroidal compoundstructurally related to the natural substrate for the biosynthesis of estrogen,androstanedione, and can be synthesized by methylidenation of androsta-1, 4-dien-17beta-ol-3-one in 6 position then oxidation of the alcohol function. Exemestane is anirreversible inactivator of the aromatase enzyme system, so inducing in vivo a dose-relatedsustained suppression of serum estrogen and minimal endocrine activity. It is the firststeroidal representative of the third-generation of orally active aromatase inhibitors with ahighly potent and selective mechanism of action, displaying good tolerability and safetyprofile. In rats with DMBA-induced mammary tumors, 10 to 100 mglkg of exemestanadministered po twice-daily for 4 weeks resulted in 76 to 88% regression. In women failinganti-estrogen therapy with tamoxifen, this agent has demonstrated high activity in locallyadvanced or metastatic disease. In addition, it may also have potential for breast cancerprevention
Inhibiting aromatase is an effective and selective method for treating hormone-dependent postmenopausal breast cancer. This is used for late-stage breast cancer in postmenopausal women, either naturally or artificially induced, where the condition has not progressed despite treatment with tamoxifen.
term of payment
TT, bitcoin
specification
100g, kg
$30.00
  • powder Exemestane CAS 107868-30-4 ,99% pure
  • powder Exemestane CAS 107868-30-4 ,99% pure
  • powder Exemestane CAS 107868-30-4 ,99% pure
  • powder Exemestane CAS 107868-30-4 ,99% pure
Desciption
  • CAS :107868-30-4
  • Molecular Weight: 296.40336g/mol
  • Molecular Formula: C20H24O2
  • Applicable to postmenopausal late-stage breast cancer with estrogen and progesterone receptor positivity
  • other english name:
  • ExeMestane(USP);ExeMestane(AroMasin);1,4-Androstadien-3,17-dione-6-Methylene-d2;(8R,9S,10R,13S,14S)-10,13-Dimethyl-6-methylene-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17(10H,14H)-dioneChemicalbook;ExeMestine;(8R,9S,10R,13S,14S)-10,13-diMethyl-6-Methylene-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione;ExeMestaneSynonyMs6-Methylenandrosta-1,4-diene-3,17-dione;PNU155971
  • Dosage 25mg once, once a day
  • Exemestane is a medication classified as an aromatase inhibitor. It is used in the treatment of hormone receptor-positive breast cancer, which is a type of breast cancer that grows in response to the hormone estrogen. Exemestane is typically used in postmenopausal women.

    Inhibiting aromatase is an effective and selective method for treating hormone-dependent postmenopausal breast cancer. This is used for late-stage breast cancer in postmenopausal women, either naturally or artificially induced, where the condition has not progressed despite treatment with tamoxifen.


    Uses antiinfective
    Uses An antineoplastic (hormonal)
    Uses Labeled Exemestane, intended for use as an internal standard for the quantification of Exemestane by GC- or LC-mass spectrometry.

    Here's how Exemestane works and what it is used for:

    1. Mechanism of Action: Exemestane works by inhibiting the enzyme aromatase, which is responsible for converting androgens (hormones produced by the adrenal glands) into estrogen. By reducing estrogen levels in the body, Exemestane helps to slow down or stop the growth of hormone receptor-positive breast cancer cells.

    2. Breast Cancer Treatment: Exemestane is often prescribed as an adjuvant treatment for postmenopausal women with early-stage breast cancer who have completed a few years of tamoxifen therapy. It may also be used in advanced or metastatic breast cancer.

    3. Hormone Receptor-Positive Breast Cancer: Exemestane is particularly effective in cases where the breast cancer is hormone receptor-positive, meaning the cancer cells have receptors for estrogen or progesterone. In such cases, estrogen stimulates the growth of cancer cells, and aromatase inhibitors like Exemestane help to block this stimulation.

    It's important to note that Exemestane is typically used in postmenopausal women. Premenopausal women may receive other types of hormonal therapy.

    Quality: Purity above 99%, directly produced by the manufacturer, can accept quality testing, and can also customize any content of powder, liquid, oil, etc.

    Transport: We can accept sea freight, air freight, and express delivery, with a guarantee time of 1-2 weeks and a customs clearance rate of over 99%. Even if the goods are detained, you can resend the freight and I will resend the goods.

    Service: We can provide sterile water for you to directly mix and inject freeze-dried powder. In addition to powder, we also have liquids, water-based agents, oils, tablets, and professional customized synthesis routes. We provide you with professional guidance on product use, product synthesis, and product customization.

    Price: We do not engage in price wars. Our first quotation may seem too expensive to you, please don't lose heart. Firstly, our quality can be guaranteed; Secondly, our transportation efficiency and customs clearance rate can be guaranteed; Thirdly, we will provide you with the highest quality service, in any aspect. If you have any questions, I will have the answer.

    Q1: Can I get some samples?

    A:Yes, we can supply the free sample, but the shipping cost be paid by our customers.
     

    Q2: How to start orders or make payments?

    A:Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union, Money Gram.
     

    Q3: How to confirm the Product Quality before placing orders?

    1.You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.

    2. You can tell us your product specifications and requests,we will manufacture the products according to your requests.


    Q4:Is there a discount?

    A:Different quantity has different discount.


    Q5: How do you treat quality complaint?

    A:Our quality control will reduce the quality problem to near zero. If there is a real

    quality problem caused by us, we will send you free goods for replacement.


    Q6:Do you Accept Sample Order?

    A:Yes, we accept small order from 2mg, 5mg and 10mg to evaluate quality of our goods.

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