Synonyms: | 11-tridecatetraenyl)-monosodiumsalt;antibioticci920sodiumsalt;antibioticcl1565asodiumsalt;ci920sodiumsalt;cl1565asodiumsalt;PHOSPHOTRIENIN;fostriecin sodium salt from streptomyces pulveraceus;FST |
CAS: | 87860-39-7 |
MF: | C19H28NaO9P |
MW: | 454.39 |
Product Categories: | Active Pharmaceutical Ingredients;FST |
Description | Fostriecin is an inhibitor of the serine/threonine protein phosphatases 2A (PP2A) and 4 (PP4) (IC50s = 3.2 and 3 nM, respectively). It less effectively inhibits topoisomerase II and PP1 (IC50s = 40 and 131 μM, respectively) and does not inhibit PP2B. Through its effects on protein phosphatases, fostriecin increases the level of histone H3 phosphorylation and may alter epigenetic regulation of cell proliferation. On a related note, fostriecin was first identified as an antitumor antibiotic. |
Uses | Antineoplastic. Fostriecin is a Topo II, PP1, and PP2A inhibitor. |
Uses | Fostriecin has been used as a protein phosphatases type 2A (PP2A) inhibitor to study its effects on phosphorylated myosin light chain (pMLC) levels in axon initial segments (AIS). It has also been used as a PP2A inhibitor to study its effects on the regulation of protein kinase Akt (pAKT) by dopamine (DA) in larval zebrafish brain. |
The potential function of Follistatin FST344 is often associated with its ability to modulate myostatin activity, making it of interest in the fields of muscle development and potential therapeutic applications for conditions characterized by muscle wasting
Here are some key points about Follistatin FST344:
Myostatin Inhibition:
Muscle Growth and Development:
Research and Experimental Use:
Administration:
Athletic and Bodybuilding Community:
Regulatory Status:
It's crucial to emphasize that the use of peptides like Follistatin FST344 for non-medical purposes is not supported by robust scientific evidence, and potential risks and side effects are not fully understood. Additionally, the legal status of such substances may vary, and individuals should be aware of and comply with local regulations.
Quality: Purity above 99%, directly produced by the manufacturer, can accept quality testing, and can also customize any content of powder, liquid, oil, etc.
Transport: We can accept sea freight, air freight, and express delivery, with a guarantee time of 1-2 weeks and a customs clearance rate of over 99%. Even if the goods are detained, you can resend the freight and I will resend the goods.
Service: We can provide sterile water for you to directly mix and inject freeze-dried powder. In addition to powder, we also have liquids, water-based agents, oils, tablets, and professional customized synthesis routes. We provide you with professional guidance on product use, product synthesis, and product customization.
Price: We do not engage in price wars. Our first quotation may seem too expensive to you, please don't lose heart. Firstly, our quality can be guaranteed; Secondly, our transportation efficiency and customs clearance rate can be guaranteed; Thirdly, we will provide you with the highest quality service, in any aspect. If you have any questions, I will have the answer.
Q1: Can I get some samples?
A:Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2: How to start orders or make payments?
A:Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union, Money Gram.
Q3: How to confirm the Product Quality before placing orders?
1.You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
2. You can tell us your product specifications and requests,we will manufacture the products according to your requests.
Q4:Is there a discount?
A:Different quantity has different discount.
Q5: How do you treat quality complaint?
A:Our quality control will reduce the quality problem to near zero. If there is a real
quality problem caused by us, we will send you free goods for replacement.
Q6:Do you Accept Sample Order?
A:Yes, we accept small order from 2mg, 5mg and 10mg to evaluate quality of our goods.