PT-141 Peptide
Overview Bremerantine PT141, also known as Bumenotide, is a drug used to treat female sexual dysfunction, and PT-141 has shown positive Chemicalbook results in a Phase I clinical trial administered in normal premenopausal women. PT141 regulates libido and sexual response by activating endogenous pathways in the brain, helping premenopausal women with low active sexual desire disorder maintain normal libido.
What is another name for PT-141?
Bremelanotide (formerly PT-141) is a synthetic analogue of α-MSH and is the active metabolite of melanotan-II (MT-II).
Specifications
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OTHER KNOWN TITLES:
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Bremelanotide
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EINECS
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211-519-9
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MOLECULAR FORMULA:
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C50H68N14O10
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MOLECULAR WEIGHT:
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1025.2 g/mol
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Packaging and Delivery
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The MOQ varies by product due to their unique specifications. We encourage you to reach out for detailed information tailored to the specific product of interest.
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Delivery schedules adapt to seasonal demands, with a 15 working day delivery time during peak seasons and 7 to 13 working days in off-peak seasons, showcasing efficient and timely delivery.
PT-141 Research
What Is PT-141?
PT-141 is the prior developmental code given name for Bremelanotide. This is a peptide originally developed as a sunless tanning agent. It is a melanocyte-stimulating hormone (MSH) that affects sexual arousal, aiding enhanced libido levels and penile erections. Unlike Viagra or Cialis, PT-141 is not a PDES inhibitor, and it does not target the vascular system. Instead, it acts on the nervous system via activation of neurons in the hypothalamus to increase sexual desire.
Does PT-141 work?
A 52-week study monitored PT 141 use in premenopausal women with hypoactive sexual desire disorder and found that the treatment remained effective for the duration of the study.
Who should not take PT-141?
Heart or blood vessel disease or. Hypertension (high blood pressure), uncontrolled—Should not be used in patients with these conditions.
How long does PT-141 take effect?
It usually takes anywhere from 2 – 4 hours to take effect. Under the direct care of a physician your PT-141 dose will be titrated to meet your exact needs. The fact that you only need one injection every 72 or more hours allows for spontaneity.
What is the bioavailability of PT-141?
The bioavailability of bremelanotide with subcutaneous injection is about 100%. Following a subcutaneous injection of bremelanotide, maximal levels occur after about one hour, with a range of 0.5 to 1.0 hours.
Does PT-141 increase blood pressure?
Many people using this medication do not have serious side effects. This medication may cause a temporary increase in blood pressure and decrease in heart rate after each injection
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1.Manufacturer or trading company? Where is the company located?
We pride ourselves on being an integrated industry and trade company, nestled in the heart of Zhengzhou, Henan Province.
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About US
Nestled in the heart of Henan Province, Zhengzhou Plastic Body Peptide Trading Co., Ltd embarked on its journey to redefine the chemical and pharmaceutical landscape. Founded on the principles of innovation, integrity, and excellence, we've dedicated ourselves to producing top-tier local anesthetics, pharmaceutical intermediates, steroids, and other crucial raw materials.
Driven by a passion for progress and a commitment to quality, our team has bridged continents, connecting with partners in North America, Eastern Europe, Southeast Asia, and beyond. Each product and solution we develop carries the mark of our rigorous research and customer-centric approach, aiming not just to meet but exceed global standards.
References
Wessells et al.Effect of an alpha-melanocyte stimulating hormone analog on penile erection and sexual desire in men with organic erectile dysfunction Urology(2000)
Gantz et al.Molecular cloning of a novel melanocortin receptor J Biol Chem (1993)
Gantz et al.
Molecular cloning, expression, and gene localization of a fourth melanocortin receptor J Biol Chem (1993)
R.C. Rosen et al.
The International Index of Erectile Function (IIEF)a multidimensional scale for assessment of erectile dysfunction Urology (1997)
J.E. Wikberg et al.
New aspects on the melanocortins and their receptors Pharmacol Res (2000)
Goldstein et al.
Oral sildenafil in the treatment of erectile dysfunction N Engl J Med (1998)
Porst et al.
The efficacy and tolerability of vardenafil, a new, oral, selective phosphodiesterase type 5 inhibitor, in patients with erectile dysfunctionthe first at-home clinical trial Int J Impot Res (2001)
