DiscoverTriptorelin---Triptorelin is a gonadotropin-releasing hormone analog .Similar to Luteinizing Hormone-Releasing Hormone.Triptorelin has been suggested to work as an inhibitor,via a synthesis of testosterone and estrogen within long-term research studies.
Unlock the potential of your health journey with Tirptorelin, an innovative solution designed to release luteal growth hormone (LH) and follicle-stimulating hormone (FSH).
With its unique dual-action formula, Triptorelin is offering a comprehensive approach to your health.
Triprerelin increases pregnancy rates in ewes by 12% to 15%6 and down-regulates the expression of GnRHR-I in the ovaries of female rats, especially in late-growing follicles.
It is an antineoplastic drug, whose pharmacological effects are same with goserelin, buserelin, and its structure is modified by natural molecular structure of the sixth L-glycine that is replaced by D-tryptophan to promote efficiency and prolong the plasmic half-life time, as well as enhance drug efficacy.
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Understanding Triptorelin
The active ingredient of triptorelin is a synthetic gonadotropin-releasing hormone (GnRH) analogue, which is also known as decapeptyl, diphereline, triptorelin acetate, gonadorelin. It is an antineoplastic drug, whose pharmacological effects are same with goserelin, buserelin, and its structure is modified by natural molecular structure of the sixth L-glycine that is replaced by D-tryptophan to promote efficiency and prolong the plasmic half-life time, as well as enhance drug efficacy. After intramuscular injection, it initially stimulates the pituitary gland to release luteinizing growth hormone (LH) and follicle-stimulating hormone (FSH).
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Aliase
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Triptorelin |
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CAS |
57773-63-4 |
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MOLECULAR FORMULA |
C64H82N18O13 |
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MOLECULAR WEIGHT |
4813.45 g/mol |
TRIPTORELIN AND TESTOSTERONE SECRETION
Studies have suggested that Triptorelin may exhibit the potential to rapidly raise testosterone levels, with long-term studies suggesting the peptide may also suppress production after chronic exposure. Scientists report that testosterone flare and has been observed in Triptorelin studies within the first few weeks. This suggests that GnRH, when specific experimental conditions, may potentially raise testosterone levels..
TRIPTORELIN AND BREAST CANCER
Hormone suppression has been considered by scientists as a potential cancer cell mitigation method in cancers sensitive to hormone levels. Selective estrogen receptor modulators (SERMs) are currently the most widely recognized substances in this context. SERMs appear to reduce the risk of breast cancer recurrence by approximately 30% – 50% depending on certain criterion in the observed research model. It is also speculated to act to shrink tumor growth, though research has speculated that tumors may become more resistant to SERMs over time. The search for SERM alternatives and excipients has led scientists to investigate the role of Triptorelin in research models of breast cancer.[1] The researchers conclude that.
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